Jurgen Klopp's men are in contention to grow to be the first English team to win all 4 main trophies in a single season.
They lifted the League Cup in February and superior to the closing four of the Champions League after surviving a overdue scare of their area-very last second leg in opposition to Benfica on Wednesday.
With Liverpool predicted to see off Spanish side Villarreal in the semi-finals of Europe's elite club competition, it is Premier League leaders City who will offer the fundamental impediment to their objectives.
City are just one factor ahead of their title rivals in the Premier League with seven video games left after remaining weekend's 2-2 draw.
Pep Guardiola's team also are within the hunt for the Champions League crown and will face Liverpool within the final in the event that they beat Real Madrid in the semis.
City have an extraordinary feat of their personal to aim for as they are looking for to end up most effective the second one English facet to win the prized treble of the Premier League, Champions League and FA Cup.
The grand goals of each City and Liverpool suggest the stakes could not be higher after they clash for the second one time inside per week, this time at Wembley for a place within the FA Cup very last.
One crew will go away the national stadium on a excessive, the other having to fast refocus.
Having closed the gap to City from a 14-factor margin in January, Liverpool are residing as much as Klopp's choice to be as "annoying as possible" to the Premier League champions.
Their league conferences this season both led to 2-2 attracts and it may take extra-time and penalties to separate them this weekend.
