The domestic group pressed tough at the start and have been rewarded after nine minutes when Amine Harit reduce in from the right, drew goalkeeper Jonas Omlin after which rolled the ball throughout the six-yard field to Bamba Dieng who shot into the empty internet.
Dieng received the penalty that doubled Marseille's lead 10 mins later.
Gerson's smart backheel gave Dieng a backyard of space, however Jordan Ferri hacked him down. Cengiz Under transformed the spot kick.
Omlin changed into despatched off in introduced time, but by means of then the healthy had lengthy been over.
Marseille received the confidence boost of a fourth instantly league win at the start of a hard week.
They tour to Greece to protect a one-purpose lead towards PAOK in Thessaloniki in an already acrimonious Europa Conference League tie on Thursday.
They visit sour rivals and runaway league leaders Paris Saint-Germain on Sunday.
"These victories deliver us momentum," stated Marseille Jorge Sampaoli.
"Now we have to recover and hope to have a few gamers back for Thursday. Then there could be the sport on Sunday with little or no coaching time."
Earlier inside the day, fourth-positioned Strasbourg's hopes of catching Marseille suffered a blow once they conceded a ultimate-minute equaliser to Lyon.